The Human 5.0 Project

Probiotics vs Prebiotics 2026: End the Gut Confusion (What Works, What Doesn’t + 7-Day Reset)

Everyone’s “fixing their gut” in 2026… and half the people are accidentally making it worse.
If you’ve ever said:“I took a probiotic and got MORE bloated,”this episode is for you.
Today on The Human 5.0 Project, we end the confusion for good:✅ What probiotics actually are (and why CFU hype is misleading)✅ What prebiotics are (and why they’re the missing piece)✅ How probiotics + prebiotics work together (synbiotics)✅ The real 2026 dose basics + why “more strains” can backfire✅ Testing that actually helps vs. expensive graphs with no action plan✅ Red flags (SIBO-style symptoms, histamine reactions, IBS triggers)✅ A simple 7-day starter plan you can run without guesswork
Medical Disclaimer: This content is for educational purposes only and not medical advice. If you have IBD, are immunocompromised, pregnant, or have severe symptoms (blood in stool, unexplained weight loss, persistent fever, anemia, waking at night with diarrhea), consult a qualified clinician before using supplements or restrictive protocols.
Drop a comment: Are you team probiotics, team prebiotics, or team “both but I’m confused”?
 
For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.
And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.
 
#Probiotics #Prebiotics #GutHealth #Microbiome #DigestiveHealth #IBS #SIBO #BloatingRelief #LeakyGut #Inflammation #Fiber #ResistantStarch #FermentedFoods #Synbiotics #Butyrate #FunctionalMedicine #NutritionScience #Biohacking2026 #Longevity #Healthspan #Human50Project #UltimateBiohacker10X

Tesamorelin (Egrifta) Explained 2026: Visceral Fat Reduction, IGF-1, Dosing Protocols & Longevity Stacks

Tesamorelin (Egrifta / Egrifta SV) is one of the most discussed “longevity-adjacent” tools in 2026—because it targets visceral fat (the fat around organs that drives metabolic aging), while stimulating natural growth hormone pulses through the GHRH pathway.
In this episode, we go origin-to-clinic:✅ What tesamorelin is (and why it’s different than straight HGH)✅ The HIV lipodystrophy approval story + what the data actually showed✅ Why longevity / functional medicine clinics are using it off-label in 2026✅ Practical dosing ranges discussed in clinics, cycling strategies, and timing✅ Popular combinations (fasting, peptides, glucose-support strategies)✅ Who tends to benefit most—and who should avoid it✅ Labs worth tracking (IGF-1, fasting glucose/A1c, lipids, waist, and more)
Medical Disclaimer: Tesamorelin is an FDA-approved prescription medication for HIV-associated lipodystrophy. This content is for education only and is not medical advice. Off-label use, dosing changes, and combinations require physician supervision. Potential risks include injection-site reactions and changes in glucose control/insulin sensitivity. Always consult a licensed clinician.
Comment below: What’s your biggest question—dosing, cycling, stacks, or whether you’re even a good candidate?Subscribe for more science-first longevity episodes. Next: The KLOW STACK
 
For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.
And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.
 
#Tesamorelin #Egrifta #EgriftaSV #VisceralFat #BellyFat #GHRH #GrowthHormone #IGF1 #Longevity2026 #Biohacking #FunctionalMedicine #MetabolicHealth #InsulinSensitivity #Prediabetes #BodyRecomposition #MenopauseHealth #Perimenopause #Healthspan #PeptideTherapy #HormoneOptimization #DEXA #CGM #FatLossScience #Human50Project #UltimateBiohacker10X

Olive Oil 2026: The Only Fat You Need, Plus Avocado & Coconut Showdown – Real Science, No Dogma

In this episode, we dive deep into the science of healthy fats, focusing on olive oil, avocado oil, and coconut oil. Discover why these oils stand out, how they impact blood sugar and overall health, and which one might be best for you. Learn practical tips for incorporating them into your diet and what to look for when choosing quality oils.
Free Download: 3-Fat Cheat Sheet with meal-pair chart and dosage guide.
 
For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.
And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.
 
#OliveOil2026 #HealthyFats #AvocadoOil #CoconutOil #NutritionScience #BloodSugarControl #MitochondrialHealth #DietTips #Longevity #Biohacking2026 #HealthyLiving

KPV Peptide 2026: The Anti-Inflammatory Powerhouse | Mechanisms, Dosing & Clinical Insights

Welcome to The Human 5.0 Project! In this episode, we dive into KPV, a groundbreaking tripeptide that’s making waves in the world of inflammation control. Discover its origins, the science behind its anti-inflammatory properties, and how it’s being explored in clinical and real-world settings. We’ll also explore dosing protocols and the latest findings from global research.
Disclaimer: This content is for educational purposes only and not medical advice. Always consult a healthcare professional before considering any peptide or experimental therapy.
 
Free Download: KPV Quick-Reference Card (Link in Description)
 
For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.
And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.
 
#KPVPeptide #AntiInflammatory #PeptideTherapy #InflammationRelief #GutHealth #SkinHealth #Longevity2026 #Biohacking #FunctionalMedicine #PeptideScience #KPV #Inflammation #IBD #Autoimmune #GutHealth #Psoriasis #MastCell #AlphaMSH #GutBrainAxis #Biohacking2026 #NoSteroids #LongevityPeptides #SystemicInflammation #CompoundedMedicine  #LongevityWarriors #TimelineExtenders #HealthspanHack #Human5.0Project

Why 97% of New-Year Diets Fail in 2026 — And the 4 Psychology Hacks That Actually Work (Science-Backed)

From identity-based habits to dopamine rewiring, we’re diving into the real science of lasting weight loss in 2026.
What you’ll learn:
The shocking stats on why most diets fail within 19 days.
How to shift from “I want to lose 20 lbs” to “I’m the kind of person who…” and why that changes everything.
How to engineer your environment and rewire your brain’s reward system to make healthy choices automatic.
Why the 66-day habit rule beats perfection every time.
If you’re ready to ditch diet culture and build lasting habits, this is your episode.
 
Free download : the 66-Day Identity Fat-Loss Calendar with exact meal timing template and weekly check-ins.
 
For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.
And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.
 
#66DayChallenge #66DayReset #HabitChange #HabitTracker #HabitBuilding #IdentityBasedHabits #WeightLossMindset #WeightLossPsychology #SustainableWeightLoss #QuitDietCulture #AntiDietCulture #NoMoreDiets #BreakTheCycle #NoZeros #ConsistencyOverPerfection #HealthyHabits #LifestyleChange #FatLossJourney #ProteinFirst #WalkAfterDinner #StrengthTraining #MetabolicHealth #Healthspan #LongevityLifestyle #BehaviorChange #NewYearReset #JanuaryReset #Human50Project #UltimateBiohacker10X

Menopause 2026: The Real Blueprint for Hot Flashes, Belly Fat, Sleep & Hormones (No Hype)

From strength training myths to fezolinetant (Veozah) and GH pathways — this is the full 2026 science-backed blueprint.
Today is the Menopause Biohacking Blueprint (2026) — the real, evidence-first playbook for hot flashes, sleep disruption, belly fat, mood swings, and brain fog. No fluff. No vendor ads. Just science — and a roadmap that actually works in the real world.
In this episode, we break down:
Why menopause isn’t “aging” — it’s a metabolic event (estrogen decline → insulin sensitivity shifts → visceral fat ↑ → muscle loss risk ↑)
The 3 non-negotiables for women 40+: muscle, insulin sensitivity, sleep
Time-restricted eating + training: what helps, what backfires, and how to avoid the “tired + puffy + wired” trap
Hormone therapy reality check: what the major guidelines actually say, and who it helps most
Non-hormonal hot flash option (FDA-approved): fezolinetant (Veozah) + why monitoring matters
The “peptide talk” — what’s promising, what’s speculative, and what belongs in the clinician lane
The bulldozer lane: prescription GH-pathway reality (powerful, but not casual)
⚠️ Disclaimer: Educational content only — not medical advice. Menopause therapies can involve prescription medications and individualized risk assessment. Talk with a qualified clinician before changing medications or trying experimental protocols.
Comment below: What’s your hardest menopause symptom — sleep, weight, mood, or hot flashes?
 
For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.
And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.
 
#Menopause #Perimenopause #MenopauseWeightLoss #HotFlashes #MenopauseRelief #WomenOver40 #WomenOver50 #HormoneHealth #Healthspan #Longevity #StrengthTraining #ResistanceTraining #MetabolicHealth #SleepOptimization #Biohacking #Human50Project #UltimateBiohacker10X #Fezolinetant #Elinzanetant #HormoneTherapy
 

Mitochondria 2026: Optimize Energy, Clear Senescent Cells & Add Healthy Decades (Science-Backed)

Today we’re going deep on mitochondria (your cellular energy engines) and senolytics (tools being studied to clear “senescent” zombie cells that sabotage recovery, inflammation, and performance). No fluff. No vendor ads. Just PubMed-backed science and what the global research is actually pointing to in 2026.
In this episode, we break down:
What mitochondria are, what they do, and why they decline with age
The lifestyle levers that reliably boost mitochondrial function (training, sleep, fasting, heat/cold)
Mitochondria-targeted nutrition + supplements (NR/NMN, CoQ10, PQQ, urolithin A, spermidine, ALA/ALCAR, olive oil polyphenols)
Senescent cells + the SASP: how “zombie cells” poison neighboring tissues
What senolytics are actually supported by human research so far (and what’s still experimental)
Peptides and advanced therapies on the 2026 watch list (MOTS-c, humanin, SS-31/elamipretide, exosomes)
A practical roadmap to apply this safely: foundation first, then targeted tools
⚠️ Disclaimer: This episode is for education only and is not medical advice. Some interventions discussed (senolytics, peptides, exosomes) may be experimental or regulated. Always consult a qualified healthcare professional before making changes—especially if you have medical conditions or take medications.
If you want the downloadable tools mentioned in the episode, check the links in the description.
Lifestyle Peptide Tracker
Senolytic Dosing Calculator
The Full 2026 Mitochondrial Optimization Guide
 
For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.
And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.
 
#Mitochondria #Senolytics #Longevity2026 #DasatinibQuercetin #NMN #PQQ #MOTS-c #SS31 #Humanin #BiohackingMitochondria #Healthspan #MitochondrialHealth #CellularAging

DSIP Deep Dive: The “Sleep Peptide” Mystery—What PubMed Shows (Insomnia, Pain, Withdrawal, Safety)

oday we’re diving into Delta Sleep-Inducing Peptide (DSIP) — the nonapeptide that’s been studied for decades in relation to sleep, stress physiology, pain, and even withdrawal states. And we’re doing this the right way: PubMed-backed facts only — no peptide-vendor hype.
In this episode:
Where DSIP came from (the 1970s origin story + sequence)
What human studies actually looked at (insomnia trials, mixed results)
Evidence for pain and withdrawal applications (older clinical literature)
Where DSIP shows up in the world’s medical literature (including DSIP-containing preparations like “Deltaran”)
The reality check: why DSIP is still considered a scientific “riddle” (mechanism/receptor gaps + dated data)
NEXT UP (you do not want to miss this): Mitochondria & Senolytics Masterclass
 
⚠️ Disclaimer: This content is educational and not medical advice. DSIP is not FDA-approved to treat any condition. If you suspect sleep apnea, depression, substance withdrawal, or other medical issues, consult a qualified clinician.
Bonus Downloads:We’ve included four free resources for this episode!
Episode Summary PDF: A concise overview of everything we covered about DSIP—perfect for quick reference.
Medical Disclaimer & Safety Notes PDF: Important information on why this is not medical advice and how to approach this topic safely.
Dosing Schedule Template PDF: A handy, clinician-supervised dosing and tracking sheet for educational use.
Dosing  PDF:  A current research dosing document, outlining dosage and administration. Download this with #2, above.
Check the links in the description to download them all!
 
For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.
And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.
 
#DSIP#DeltaSleepInducingPeptide#Biohacking#SleepOptimization#LongevityScience#PeptideTherapy#SleepResearch#HealthPodcast#Human50Project#UltimateBiohacker10X#ScienceNotHype#WellnessCommunity#InsomniaSolutions
 

Winning the Longevity Race: Mindset Shifts & Sustainable Habits for 100+ Healthy Years (2026)

Longevity isn't about chasing magic pills — it’s a race won through paradigm shifts, embracing discomfort, and sustainable habits. In this episode, Ultimate Biohacker 10X breaks down why food is medicine, why women should lift heavy (busting the "bulky" myth), how to reframe exercise and nutrition, and practical 2026 strategies for healthspan.
Key insights:
Food as drug: Quality fiber, protein, and polyphenols for microbiome and inflammation control.
Strength training myths: Women gain metabolism, bone density, and hormone balance — not bulk.
Embracing discomfort: Small stresses (cold, fasting, heavy lifts) build resilience.
Sustainable roadmap: Incremental wins, tracking biological age, community support.
2026 trends: Fiber diversity, oral health as an aging metric, GLP-1s as tools — not crutches.
Download the free Longevity Race Roadmap PDF (habits, tracking, mindset tools)
 
For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.
And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.
 
#Longevity #Healthspan #Biohacking #LongevityMindset #StrengthTrainingWomen #SustainableHabits #EmbraceDiscomfort #AntiAging2026 #MicrobiomeHealth #FiberForLongevity #WomenBiohacking #ParadigmShift #HealthyAging #Human50Project #UltimateBiohacker10X

The Longevity Dilemma: Biohacking Hype vs Real Science (How to Trust But Verify in 2026)

Welcome back to The Human 5.0 Project with Ultimate Biohacker 10X! In this episode of the  Podcast, we dive into "The Longevity Dilemma: Navigating Biohacking Hype vs. Evidence-Based Science."
In a world buzzing with cutting-edge tech, peptides, and supplements, it’s easy to get lost in the hype. From miraculous claims of instant youth to peptides that promise to melt fat effortlessly, we’ll explore how to separate the real science from the marketing noise.
In this episode, you'll learn:
The psychology behind why we’re drawn to quick fixes and shortcuts.
Practical tools to evaluate the credibility of longevity claims.
How to distinguish between anecdotal evidence and rigorous scientific data.
The importance of embracing patience and foundational habits for true longevity.
A simple, actionable checklist for spotting wellness hype and making informed decisions.
Disclaimer: This content is for educational purposes only and not medical advice. Always consult with a qualified healthcare professional before making significant changes to your health regimen.
Join the conversation and share your experiences! Let us know what biohacks you’ve encountered and what actually worked for you.
 
For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies.
And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.
 
#Longevity #Biohacking #HealthScience #Peptides #Nootropics #CriticalThinking #EvidenceBased #Wellness #LongevityLifestyle #HumanPerformance #TheHuman50Project #UltimateBiohacker10X #TrustButVerify #ScienceVsHype #HealthJourney #InformedDecisions